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Hollywood's 10 Most Successful On-Screen Pairings

When the Right Chemistry is in Place, One Plus One Equals Big Box Office Hit

The box office figures on the list, from Box Office Mojo, are not inflation-adjusted. As such, none of Old Hollywood's iconic pairs, like Vivien Leigh and Clark Gable, or Jerry Lewis and Dean Martin, make the cut. Films where three primary characters share the spotlight ( Shrek, Harry Potter) were also excluded. Tom Hanks and Meg Ryan, who memorably united for three films ( Joe Vs. the Volcano, Sleepless in Seattle, You've Got Mail) fell short, banking $518 million. They were, surprisingly, edged out by Crocodile Dundee co-stars (and marrieds in real life) Paul Hogan and Linda Kozlowski. The three Dundee flicks grossed $607 million.

Cartoon characters also clinched a spot on the list. Tom Hanks and Tim Allen provide the voices for Woody and Buzz Lightyear, respectively, in the Pixar-produced, Walt Disney-distributed 1995 blockbuster animated feature Toy Story, which grossed $354 million. Four years later, the pair reprised their roles for a sequel that booked $485 million worldwide. Hanks and Allen may soon move up the list of Hollywood's Most Successful On-Screen Pairings. They are at work on a third Toy Story sequel, slated for release in 2010.

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