In 2008, Brenda, now a successful theater actress and stage director, returned to the reprised "90210" to direct the high school musical. Earlier this year, Doherty competed on "Dancing with the Stars," but was eliminated with partner Mark Ballas in the second week.
Recently the actress, who is dating photographer Kurt Iswarienko, denied rumors that at 39 she is expecting her first child. "I was never pregnant and not fat," she wrote on Twitter.
Tiffani Thiessen/Valerie Malone:
After Doherty left the series, Thiessen joined the cast as the new vixen, Valerie Malone, after Thiessen's series "Saved by the Bell," where she played popular cheerleader Kelly Kapowski, ended.
A former neighbor of the Walshes, Val quickly shed her tame Midwestern manners (and the Kelly Kapowski typecast) and picked up where boisterous Brenda had left off. In real life, Thiessen and co-star Brian Austin Green began a seven-year romance that continued after Thiessen left the series in 1998. When that ended, Thiessen began seeing "Suddenly Susan" actor David Strickland, until he committed suicide in 1999.
Now, married to actor Brady Smith, Thiessen says she has the best of both worlds, a career and a fmily. On location in New York for the second season of "White Collar," she told a reporter, "It's a very different season for me than it was last year. Because I couldn't travel or fly because I was really, really pregnant when the season started...I shot here in Los Angeles on a studio with a green screen behind me."
Jennie Garth/Kelly Taylor
After landing her first starring role in "Growing Pains," Garth joined the original cast of "90210" and stayed through the end, winning a Young Artist Award along the way.
Garth played the popular teen queen Kelly Taylor, who faced some serious problems, including competing with Brenda for Dylan's affection. In the series' finale, Kelly reunited with Dylan. In real life, Garth has three daughters with actor Peter Facinelli.
When the new "90210" was announced, Garth, who starred alongside Amanda Bynes in the sitcom "What I Like About You," was one of the first original cast members to sign on. Garth's character Kelly is now a guidance counselor at West Beverly High.
Tori Spelling/Donna Martin
Ever since Spelling landed the role of Donna Martin on "90210," a series co-produced by her father, the famed television producer Aaron Spelling, she has fought to be seen as more than just a spoiled rich girl.
Spelling played naive and ditsy Donna, whose prim demeanor was a stark contrast to Brenda's. At the series' end, Donna remained a virgin, tying the knot with longtime love David.
Soon after Spelling joined "90210" she was on her own financially, she told ABC's "20/20." "I had a hit TV series, so I didn't really need [my parents] for anything," she said.
That changed when "90210" went off the air. Spelling says that at one point she owed hundreds of thousands of dollars on her credit card and that she came close to bankruptcy, all because of her "bad shopping habits."