"Harry Potter and the Deathly Hallows, Part 1" managed to avoid getting tangled up in the fierce holiday competition and remained the No. 1 film in America, earning an estimated $50.3 million.
Disney's "Tangled," which came in second with an estimated $49.1 million.
The penultimate film in the "Harry Potter" franchise has now raised its domestic total to $220.4 million after just 10 days in theaters, according to The Associated Press.
"Tangled," starring Mandy Moore as the voice of princess Rapunzel in the modern take on the classic fairy tale, raised its total gross to $69 million since opening on the Wednesday before Thanksgiving.
On its opening weekend, "Deathly Hollows" earned an estimated $125.1 million, which topped the previous leader in the Harry Potter franchise, 2005's "Harry Potter and the Goblet of Fire," which took in $102.7 million in its first weekend, to become the sixth-biggest opening weekend of all time.
"Burlesque," the bawdy vehicle for pop stars Christina Aguilara and Cher -- who hasn't appeared on the big screen since 2003 -- survived a critical beating to earn $11.8 million over the weekend, raising its tally since Wednesday to $17.2 million.
Also landing in the top 5 was Dreamworks' animated feature "Megamind," which brought in $12,850,000 in its third week of release to rack up a $130.4 million total, and the Denzel Washington action film "Unstoppable," which took another $11.7 million to inch above the $60 million mark in total earnings.
Anne Hathaway and Jake Gylenhaal's romantic comedy, "Love and Other Drugs," which went into wider release this weekend, took in $9.8 million on just over 2,400 screens.