Hollywood's It Girls: Nine Rising Stars

Edward Zwick cast her in 2009's "Defiance," about a group of Polish Jews banding together to escape the Nazis. Upcoming roles include everything from the lead in Tim Burton's "Alice in Wonderland" to a turn as the love interest in Gus Van Sant's next film.

Evan Rachel Wood

Evan Rachel Wood, 24, mesmerized audiences in Catherine Hardewicke's "Thirteen," a tour de force of teenage angst, but it was her role in Darren Aronofsky's "The Wrestler," as Mickey Rourke's estranged daughter, that distinguished her.

She continues on her trail of off-the-beaten-path roles with "Spider-Man," the upcoming Broadway musical.

The March Hollywood Issue of Vanity Fair hits newsstands today in New York and Los Angeles and nationally Feb. 9.

ABC News' Luchina Fisher contributed to this article.

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