The new movie "The Heartbreak Kid" is Ben Stiller's first collaboration with directors Peter and Bobby Farrelly since their raunchy breakaway hit "There's Something About Mary."
"Once every nine years, I can take it," Stiller told "Good Morning America" entertainment correspondent Cat Deeley.
In the latest Farrelly brothers romp -- a remake of a 1972 film starring Cybill Shepherd and Charles Grodin -- Stiller plays a bachelor who thinks he's finally met the woman of his dreams. On the honeymoon, though, he discovers his new bride is a nightmare, and he meets another woman and falls in love.
Filming with the Farrellys is all about fun, Stiller said.
"It's very loose, you hardly ever rehearse and you'll do a crazy sex scene and then they'll play a crazy practical joke," he said.
When pressed about what kind of practical jokes, Stiller said he couldn't go there.
"I can't even talk about the jokes they play, they are so horrendous. I don't want talk about it in the morning."
The 41-year-old father of two said the Farrellys will push the envelope as far as it goes.
"Yeah, there are things that I've told them I won't do, usually involving exposing some part of my body," he said.
The buzz surrounding the film has been positive. Stephen Spielberg even came to visit the Dreamworks set, which Stiller said immediately changed the mood.
"Everybody's sort of like, 'Oh my God, this is my big chance right now.' People who have been in the business for 30 years, this is the moment I've been waiting for, they're doing another 'Indiana Jones,' right?" Stiller said.
Stiller's friend and frequent collaborator Owen Wilson is out of the hospital and lying low after a recent suicide attempt. Wilson dropped out of Stiller's project "Tropic Thunder" and was replaced by Matthew McConaughey.
"He's a really good friend, and I think he's doing well," Stiller said of Wilson, adding, "I'd like to keep that private. I think he's entitled to his privacy."
Movies have always been a family business for Stiller, who has worked with both of his famous actor parents, Jerry Stiller and Ann Meara, in films. In "The Heartbreak Kid," his father joins in the naughty fun.
"It's fun to sort of hear the things coming out of his mouth in the film," Stiller said. "Because he has this sort of, has this … I don't know how you describe it, this garbage mouth."
In one funny scene in the movie, Stiller's character and his new wife, played by Malin Ackerman, are honeymooning in Mexico, when Stiller becomes enraged by a very persistent mariachi band serenading the tense couple with a manic version of "La Cuchuracha."
Deely asked how Stiller is able to so easily tap into that rage. Where does it come from?
"I don't know," he said. "You'd have to talk to professionals about that."