It's due to that "endless" media attention that Conway believes it will be virtually impossible to find a jury that is unfamiliar with the case.
"It's been so publicized that if I can find somebody that knows absolutely nothing about it, they probably don't know much about anything else," Conway said.
While moving the case from Orlando, Florida to Miami may help, as the defense has suggested, Conway said it would still be possible to pick a fair jury, as long as pre-trial motions can keep "critical evidence" from being released and speculated upon.
The comment came days after prosecutors released 1,000 pages of discovery documents connected to the case which detail everything from Casey's work history to a conversation Cindy Anthony allegedly had with a blogger in which she implies Casey was in some way responsible for Caylee's disappearance -- something Conway said never happened.
Last week reports emerged that a crime blogger claimed Casey Anthony told him Casey "did something" to Caylee -- a claim Conway said the defense will be able to prove is false.
"There were also e-mails that were hacked into and purported to be Cindy's," Conway explained. "She did not say that."
Conway also downplayed documents that suggested Cindy and George may have believed Casey was not fit to be a parent.
"George and Cindy have characterized Casey as a good mother. She's a young mother and every parent makes mistakes," he said. "Were there arguments? Sure there were. But there's a lot of love in that family and there still is.
"There was never any threat or idea that they [George and Cindy] would try to remove Caylee from Casey," he said.
The couple's statements have not always been beneficial to Casey's case. Just days after Casey was arrested for child neglect, a frantic 911 call from Cindy Anthony was released in which she said a car driven by Casey smelled "like there's been a dead body in it."
Cindy Anthony later recanted the statement, saying the smell could have been old pizza, but Conway said the Anthonys do regret the way the statements came out.
"Their regret is that it's out there in the public domain and they don't have the ability to explain the story in full," Conway said. "[They] can't take it back. The only way to maintain her right to a fair trial is to be quiet about it until this is in front of a judge and a jury and they can tell the whole story."
In the meantime, Conway and Baez are expected to make several more motions concerning the release of evidence, both to give a new addition to the defense team, death penalty specialist Andrea Lyon, time to prepare for the trial and to spare the "fragile" Anthony's from repeated media reports about their dead granddaughter.
"What they don't want to hear about for the next year is everybody's speculation about how Caylee died because there is no cause of death," he said.
After the body was found George Anthony contemplated suicide and Cindy Anthony admitted to having similar thoughts herself, Conway said.
"It's been a horrible year," he said.