Regarding safety of baked milk for the children who could tolerate it, growth and intestinal permeability followed for 12 months showed no adverse effects.
Eosinophilic esophagitis developed in two active-group children (2.3 percent). One couldn't tolerate baked milk and had been strictly avoiding milk at the time of diagnosis. The other developed the esophagitis after successfully downing unheated milk in the food challenge but didn't improve after all forms of milk were eliminated from his diet and milk was reintroduced safely.
In the comparison group, the rate of eosinophilic esophagitis was 8.3 percent despite all the children being on a strict milk-avoidance diet.
Despite the apparent safety of this approach, Sampson and other leading allergists have warned families not to try baked-milk food challenges at home.
Food challenges in the study were done under medical supervision in carefully controlled conditions so that any severe reactions could be treated quickly before serious harm occurred.