What Is Nateglinide And Repaglinide, And When Are They Used?

Question:What is nateglinide and repaglinide, and when are they used?

Answer:Nateglinide and repaglinide are two newer category of agents that can act in a very similar manner to the sulfonylureas drugs. Their benefit, or their advantage, is that they act for a much shorter time period than the sulfonylureas. Whereas the sulfonyureas may act a full 24 hours, and put you at greater risk for hypoglycemia, or low blood sugars, if you skip a meal; this category of drugs, repaglinide and nateglinide, actually act much shorter.

You take them just before you're about to eat your meal, and their effect is essentially gone within a couple of hours of finishing your meal. These agents may be more beneficial in older patients that may be skipping meals, or anybody that has a more irregular meal schedule. side effects, though, remain similar to sulfonylureas, in that you still may get a hypoglycemic episode, and you may get some weight gain with these agents.


Next: What Is Acarbose (alpha-Glucosidase Inhibitor) And When Is It Used?

Previous: What Are DPP-IV Inhibitors And When Are They Used?

-- This embed didnt make it to copy for story id = 3826550. -- This embed didnt make it to copy for story id = 3826550. -- This embed didnt make it to copy for story id = 3826550.
Join the Discussion
You are using an outdated version of Internet Explorer. Please click here to upgrade your browser in order to comment.
blog comments powered by Disqus
You Might Also Like...
See It, Share It
PHOTO: Oscar de la Renta and Oprah Winfrey attend the Costume Institute Gala Benefit to celebrate the opening of the American Woman: Fashioning a National Identity exhibition at The Metropolitan Museum of Art, May 8, 2010, in New York City.
Rabbani and Solimene Photography/WireImage/Getty Images
PHOTO: Up in Ash: Mount Sinabung Erupting
Tibt Nangin/Anadolu Agency/Getty Images
PHOTO: Firefighters rescue a woman who got stuck in a chimney in Thousand Oaks, Calif.
Ventura County Fire Department
PHOTO: Apple Pay is demonstrated at Apple headquarters on Oct. 16, 2014 in Cupertino, Calif.
Marcio Jose Sanchez/AP Photo