Celeb Rehab: Are Genes or Fame to Blame?

Addiction experts say both genes and environment are at play in drug abuse.

ByABC News
June 2, 2008, 5:33 PM

June 3, 2008 — -- Actress Tatum O'Neal, who was arrested Sunday after allegedly buying cocaine on a New York City street corner, says the cops who arrested her may have saved her life.

"I'm still sober!" O'Neal told The New York Post after she was released from jail Monday. "Just when I was about to change all that and wreck my life, the cops came and saved me."

Tatum, whose battles with addiction have been well chronicled in the tabloids and in her own memoirs, is another in a long conga line of celebrities who have attributed their drug addictions, in part, to the struggle to adjust to the pressures of childhood fame.

Tatum won an Oscar at age 10 for her role, opposite her father, in the movie "Paper Moon."

But O'Neal's struggle with substance abuse suggests that her rescue from a repeat encounter with drugs may only be the beginning of a larger battle, and may have as much to do with genes as it does with celebrity, experts say.

O'Neal described her trajectory from child stardom to treatment for addiction in her 2004 memoir, "A Paper Life." As the youngest person to win an Academy Award, the daughter of an alcoholic actress and child sidekick to her father, famous party-boy actor Ryan O'Neal, she may seem typecast for the part of a star struggling against tough odds to stay clean.

But is an alcoholic family and fame really a recipe for drug addiction?

Dr. Timmen Cermak, president-elect of the California Society of Addiction Medicine, tends to think of inheriting an addiction as an analogy of sunburn risk. In short, he says, a person with fair skin only needs a low amount of sun exposure before burning, while a person with darker skin could be exposed more before he or she is burned.

"It's no different than sunburn," says Cermak. "Every one of us has a limit to how much we can use, or be exposed to, before we become addicted that risk is different for different people."

Famous or not, O'Neal was right that her parents' being addicted increased her own risk of becoming addicted, Cermak says.

"We have very good evidence that heredity plays a significant role," says Cermak, who explains that even if a biological child of an alcoholic was adopted and raised by non-alcoholics, statistically that child is four to nine times more likely to become an alcoholic than the general population.

Thomas Kimball, associate managing director of the Center for the Study of Addiction and Recovery at Texas Tech University in Lubbock, Texas agrees.

"The best research that we have to date suggests that there's a strong genetic influence that is concerned," says Kimball. "But it's complicated because the genes that have to line up are complex: If your mother is an addict, it doesn't mean you're going to be an addict, but there's a higher probability."

As the experts increasingly describe addiction as a disease with both environmental and genetic components, looking to both a person's blood and his or her social situation can help explain why addictions form.

"Anytime a disease process is manifest, it's going to have genetic, environmental, or social factors feeding it," says Kimball.

Thus enters the social factor, and as the child of Hollywood stars, O'Neal had a unique experience. The actress described the drug culture that influenced her childhood in an interview with CNN's Larry King.

"It was not just my father, but it was around where I was growing up. I mean, it's always been around me," O'Neal says about growing up around drugs and booze.

If high drug use and alcohol become the social norms, Cermak says, conceptions of limits become skewed. "It's the same question that all of us have: What is my limit and am I willing to live within that limit."

"Clearly if you are socialized in a family, in a community that is a high-drinking or high drug-use, then that becomes the norm to you," Cermak says.