In general, female partners of male childhood cancer survivors weren't at increased risk for pregnancy complications, the study found. However, women did have a higher risk of preeclampsia if their male partner had certain types of childhood cancer, especially brain tumors.
"Most pregnancies resulting in live births among partners of male childhood cancer survivors were not at significantly greater risk of complications versus comparison subjects. However, our findings of increased low birth weight and preeclampsia associated with some diagnostic groups raises the possibility that prior cancer therapy may affect male germ cells (cells that will become sperm) with effects on female partners and progeny of male survivors," the study authors concluded.
The Nemours Foundation has more about childhood cancer.
SOURCE: JAMA/Archives journals, news release, Oct. 5, 2009