FDA Warns of Fracture Risk with PPIs

Proton pump inhibitors (PPIs) may increase the risk of fractures of the hip, wrist, and spine with high-dose or chronic use, the U.S. Food and Drug Administration warned Tuesday. Labeling on drugs in this class -- both prescription and over-the-counter -- will change to reflect this risk, the agency said. Prescription PPIs include esomeprazole (Nexium), dexlansoprazole (Dexilant), omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), and rabeprazole (Acihpex). The...Full Story
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