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10 Baffling Medical Conditions

Despite Researchers' Efforts, These Conditions Remain Clouded in Mystery

Persistent Sexual Arousal Syndrome

For those who have never experienced persistent sexual arousal syndrome, or PSAS, its symptoms may seem more like a godsend or a dirty joke than a debilitating condition.

However, for the women who experience PSAS -- which causes them to live perpetually at the brink of orgasm -- the condition is a nightmarish curse. And up until 2001, it was a curse that didn't even have a name.

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"I thought I was alone in this," Heather Dearmon, a 34-year-old South Carolina woman who experiences PSAS, told ABC News' "Primetime." "And this is after seeing every kind of doctor imaginable -- gynecologist, psychologist, psychiatrist — you know, everything. And none had ever heard of anything."

Relief from the condition is often as elusive as sympathy. The sensations, which are not brought about by fantasies or other sexual thoughts, are often only partially relieved through orgasm. For some women, even sex does not help quell their arousal, and on occasion can even make the sensations worse.

Dr. Irwin Goldstein, a professor of surgery at U.C. San Diego and the head of the Sexual Health Program at Alvarado Hospital, studies the condition. And he says understanding of the condition is spare, even within the medical community.

"Every lecture I give on this, there's always smirks in the audience: 'oh I wish my wife was like this.' These are professional physicians," Goldstein said. "And I said, 'no, no, you're, you don't really want this. You do not want your wife to have this, please.'"

Indeed, the mortifying nature of PSAS leads Goldstein to believe that perhaps thousands of women suffer from the condition without seeking a doctor's help.

"To me this is a sickness," Dearmon said. "This is not, it's not something we've chosen. ... I would rather never have another orgasm in my life for the rest of my life than to have this problem."

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