DeBroff and her brother spent two decades "working through the intensity of the loss" and recommend parents have wills and all legal directives about guardianship in place -- with or without children.
"The last thing you want is for a court to decide who raises your kids and run the risk that they get placed in foster care pending a resolution."
She said when couples split flights, it "acts as a powerful insurance policy."
Meanwhile, Nancy Pankiewicz, a crash survivor, is still a bit nervous, but prepares her family before they fly, always checking for the emergency exits before take-off.
"I guess we always thought, what are odds of that happening again?" she said. "They are pretty slim, and it's totally out of your hands."
To learn more about directives for families traveling domestically or overseas, go to Forms4Parents.com.
Additional reporting by ABC's Sabina Ghebremedhin.