An independent panel of forensics experts concluded that the bra clasp had been left on Kercher's bedroom floor for nearly a month after the murder, had been mishandled and likely contaminated. The speck on the knife was so minute it could not be retested and could have come from another substance.
If the supreme court rules today that Knox should not have been exonerated, a new trial would be ordered in a lower court. Knox would not be required to return to Italy for the proceedings.
If that lower court trial convicted her again, the verdict would again be appealed to the Supreme Court. Only if the Supreme Court upholds the lower court's guilty verdict could extradition proceedings begin to return Knox to Italy, although experts do not believe such an effort would be successful.
Since her 2011 release from prison, Knox has resumed her life in Seattle, taking classes and spending time with her family and boyfriend, James Terrano.
Her memoir,"Waiting to Be Heard," published by HarperCollins, will be released April 30. She reportedly received an advance of $4 million for the book.
Knox's first interview since she was freed will air during a primetime special on Tuesday, April 30 at 10 p.m., ET on the ABC Television Network.