When asked if there's a double standard when it comes to likeability she said, "I think that's the world we live in. I understand that. I accept it, but I don't let it deter me. I just think here that we're going to overcome that."
The Clinton campaign said that the men campaigning don't have to answer similar questions regarding their likeability. And despite the questions regarding her personal charm, ultimately Clinton believes voters will look at her record. "We've gone through trying to decide, who would you rather have a beer with, and look at the results. I think we want to say, well, who would be the best president?
"We're going to break the highest glass ceiling, for not just me, but for all girls and women. ...You know that wonderful old line about women do everything? It's like Ginger Rogers did everything Fred Astaire did, only backwards and in high heels. Well, we just have to go out and do it. There's no point in worrying about it."
"I think the campaign is doing very well," Clinton told "Nightline" co-anchor Cynthia McFadden. "There's a rhythm to campaigns. I know that. I've been in a lot of them over the course of my life. It's really picking up steam, and that's what I feel."
Watch Cynthia McFadden's interview with Hillary Clinton tonight on "Nightline" at 11:35 p.m. ET.
Clinton's national numbers are still overwhelming. Eighty-one percent of the voters surveyed suggest that she has the best leadership skills to run this country. Clinton acknowledged that her numbers aren't as impressive in Iowa and New Hampshire, states where she's been spending the most time, but said "that's just the pattern of elections."
And in response to a question by a reporter in Iowa this week, Clinton said, "I've got my groove back," helped in part by an endorsement from The Des Moines Register.
"[The endorsement] helped a lot, and it helped for a very clear reason, because it was carefully thought through," she told McFadden. "It was focused on what's important. ... obviously I'm honored and humbled to have gotten their endorsement, because it really makes the case for my candidacy. "
An ABC News/Washington Post poll out in Iowa today showed almost no change in overall numbers from the poll in November, with Clinton and Barack Obama essentially neck-in-neck and Edwards not far behind.
Does Clinton believe that demonstrates that the "Oprah Effect" wasn't as significant as expected? "I think that we are all lucky to have supporters, from our spouses to high-profile celebrities and it's great to have them raising visibility and excitement," she said.
"But...voters are going to decide among human beings, among each of us as candidates, based on our record, our experience, our qualifications, our vision, our plans for the future."