Oct. 13, 1999 -- U.S. Senate refuses to ratify the Clinton-signed Comprehensive Test Ban Treaty, which would have forbid nuclear weapons testing.
Sept. 2, 1999 -- The Clintons purchase a home in Chappaqua, N.Y., north of New York City.
Feb. 4, 2000 -- Announces the U.S. economy has set a record for its longest uninterrupted economic expansion.
April 22, 2000 -- Federal agents seize Elian Gonzalez, a 6-year-old Cuban refugee boy, in a raid on the Miami home of his relatives. Officials eventually return Gonzalez to his father's custody in Cuba, angering many U.S.-based Cubans.
July 13, 2000 -- United States and Vietnam normalize trade relations.
Oct. 10, 2000 -- Clinton signs bill to grant permanent normal trade relations with China.
Oct. 12, 2000 -- Terrorists attack the USS Cole in a Yemeni port, blowing a hole in the side of the ship and killing 17 sailors.
Nov. 7, 2000 -- Hillary Clinton is elected to represent New York state in the U.S. Senate. Turmoil involving the vote in Florida leaves presidential race between Gore and Republican Texas Gov. George W. Bush unresolved, though Bush eventually emerges as the winner.
Nov. 17, 2000 -- Clinton arrives for the first official state visit to Vietnam by a U.S. president.
Jan. 20, 2001 -- On his last day in office, Clinton grants pardons to dozens of people, including Marc Rich, a commodities trader living in Switzerland to avoid prosecution on numerous charges.
April 2001 -- After controversy over the public expense of proposed office space in downtown New York City, Clinton instead opts for less-expensive office space in the Harlem neighborhood.
June 9, 2003 -- Hillary Clinton's memoirs, "Living History," are published.
June 22, 2004 -- Clinton's memoirs, "My Life," are published.
Sept. 6, 2004 -- Undergoes heart bypass surgery in New York City.
Fall 2004 -- Clinton stumps for unsuccessful Democratic presidential candidate Sen. John Kerry, D-Mass.
Nov. 18, 2004 -- Dedication and opening of William J. Clinton Presidential Center and Park in Little Rock, Ark.
December 2004 -- Teams with former President George H.W. Bush to lead the U.S. response to the 2004 tsunami in the Indian Ocean.
May 3, 2005 -- Joins forces with a fellow former Arkansas governor, Mike Huckabee, a Republican, and the American Heart Association to launch a campaign against childhood obesity.
Dec. 27, 2005 -- Clinton and President George H.W. Bush are named ABC News' people of the year for their relief efforts on behalf of victims of the Indian Ocean tsunami and Hurricane Katrina.
February 2006 -- Tours India as part of his efforts to fight world AIDS.
Jan. 26, 2008 -- Sparks controversy by explaining Barack Obama's success in the South Carolina Democratic presidential primary against his wife, Hillary Clinton, by citing an earlier African-American candidate's record there: "Jesse Jackson won South Carolina in '84 and '88. Jackson ran a good campaign. And Obama ran a good campaign here."
July-August 2008 -- Tours African nations with daughter Chelsea Clinton to observe humanitarian work by the Clinton Foundation.
May 19, 2009 -- Appointed the United Nations special envoy to Haiti.
Aug. 4, 2009 -- Returns from a surprise trip to North Korea after securing the release of jailed U.S. journalists Laura Ling and Euna Lee.
Jan. 12, 2010 -- Major earthquake strikes Haiti, to which Clinton is the U.N. special envoy.