An alternative presented by some, including GOP Sen. Olympia Snowe, is a "trigger" mechanism, by which a public option would come into play if private insurance companies fail to provide affordable coverage to Americans.
Tort Reform: Republicans want to see measures implemented that would give doctors some protection against medical malpractice lawsuits, and cut their costs.
Cost: Obama has said he will not sign a bill that adds to the deficit, but Republicans are not convinced. Instead, GOP leaders are lashing out at Democrats' proposed cost cuts in Medicare and Medicaid.
"Even if they were able to make it deficit-neutral -- which the American people don't believe is possible and most of us are skeptical about -- you're looking at a minimum of $400 billion of cuts in Medicare, not to make Medicare more sustainable, not to make it solvent somewhere in the future, but to transfer those funds to those who are currently uninsured," said Senate Minority Leader Mitch McConnell, R-Ky.
ABC News' Jonathan Karl and Z. Byron Wolf contributed to this report.