Obama finishes the weeklong trip with a stop in Accra, Ghana, where he will meet with President John Atta Mills, address members of parliament and tour Cape Coast castle, an old slave fort where hundreds of thousands of Africans were held before boarding slave ships.
The White House chose Ghana over other African nations, including Kenya, where his father was from, to showcase a successful African democracy. Ghana has held peaceful democratic elections, including Mills' election earlier this year
"Ghana is a truly admiral example of a place where governance is giving a stronger, thriving democracy," said Michelle Gavin, special assistant to the president and senior director for African affairs. "Far too often discussions about Africa are focused on crisis. And Ghana is not in crisis. It's an example for the region and more broadly."
On the agenda for the meeting with Mills are agricultural development, food security, maternal mortality numbers, and regional issues relating to stability, governance and counternarcotics.
ABC News' Yuni de Nies and Sunlen Miller contributed to this report.