Robert Kennedy's body was flown to New York, where it lay in St. Patrick's Cathedral for mourners to come and honor the fallen presidential hopeful.
Sen. Kennedy delivered an emotional eulogy at the funeral mass on June 8, 1968, saying of his brother, "As he said many times, in many parts of this nation, to those he touched and who sought to touch him: 'Some men see things as they are and say why. I dream things that never were and say why not.'"
Later that night a private train transported his body from New York to Washington, where he was laid to rest in Arlington, just a few yards from the gravesite of his older brother.
John F. Kennedy Jr., Sen. Kennedy's nephew, had an emotional burial at sea after he, his wife Carolyn and his sister-in-law Lauren Bessette were killed in a plane crash off the coast of Martha's Vineyard on July 19, 1999.
In the weeks afterward, Americans filled the streets of New York to grieve at planned and makeshift memorials for the crash victims.
Again, it was Sen. Kennedy who gave the eulogy at his nephew's memorial, lamenting, "From the first day of his life, John seemed to belong not only to our family, but to the American family."
At the John F. Kennedy Presidential Library in Boston, Mass., condolence books made available early today morning for museum visitors to sign in Kennedy's memory were already being filled with messages.
"He was a champion of the common man and left a great legacy of 46 years in the Senate," wrote Anlee and Bob Schaye of Newton, Mass. "He will be sorely missed."
Flower arrangements and photographs of Sen. Kennedy and his brothers flanked the books.
Allen Karot of Canton, Mass., wrote, "There will be no one who will be as passionate as Sen. Ted Kennedy was in fighting for all of us in Massachusetts."
Kennedy is the eighth of the nine children of Joe and Rose Kennedy to die. Following the senator's death, only one Kennedy sibling -- Jean Kennedy Smith -- survives.
Tribute areas honoring Kennedy are being set up at The John F. Kennedy Presidential Library and Museum in Boston, the JFK Museum in Hyannis, Mass., and Kennedy's Washington Office. In lieu of flowers, the family has requested donations be made to educational programming at the Edward M. Kennedy Institute for the United States Senate.