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After voting at a Chicago school, Obama spent the morning campaigning in Indiana before returning to Chicago to conduct television interviews broadcast via satellite to the swing states of Florida, Pennsylvania, Colorado, Virginia, Ohio, North Carolina, Nevada and Missouri.
Obama voted with his two young daughters in Chicago before he plunged into a final round of campaigning in Indiana.
"I voted," the Democratic presidential candidate said, holding up the validation slip he was given after turning in a ballot at the Shoesmith School in his Chicago neighborhood.
Obama voted at the same polling station as William Ayers, the former 1960s radical who became a flashpoint in the campaign when Palin accused Obama of "palling around" with a domestic terrorist.
Sarah Palin, McCain's running mate, voted in her hometown of Wasilla and then joined McCain in Phoenix to watch the results.
After voting, Palin noted that the result would be historic, implying that the voters would elect either the country's first black president or the first female vice president.
"It bodes so well the progress our country is making," she said.