One of the biggest disappointments was the number of women voters who did not stick with the only female candidate in the race, and voted for Obama instead.
Obama beat Clinton among women voters in Iowa — garnering 35 percent of the female vote to her 30 percent.
Clinton's Iowa campaign had been banking on support from women, particularly older women. The senator made a strong pitch to women — talking about women's rights and repeatedly telling the story of little girls who would be inspired by her example and hope to be president one day.
Her campaign ran ads featuring Clinton's daughter and mother. They trotted out old friends who talked about Clinton's warmth and caring.
Ellen Malcolm, the founder of Emily's List and a Clinton supporter who stood on stage with her in Des Moines, said Clinton may have been hurt because older women could not make it to the caucus sites. Younger, working-class women may have been working and unable to attend.
The Clinton campaign is hoping it will have better luck in New Hampshire and the 24 states that vote Super Tuesday, Feb. 5.
Clinton proclaimed herself "confident and optimistic."
"You know we have always planned to run a national campaign all the way through the early contests," Clinton said at one point on stage in Des Moines.
Still, it would have been nice to land in New Hampshire this morning with a victory under her belt … instead of a loss.