At age 61, Elizabeth Edwards lost her six-year battle with breast cancer on Dec. 7, 2010. Edwards, who is estranged from her husband and one-time presidential hopeful John Edwards, was first diagnosed with breast cancer in 2004. Here, Edwards arrives at the "Stand Up To Cancer" television event at Sony Studios in Culver City, Calif., Sept. 10, 2010. (Matt Sayles/AP Photo)