The Tea Party movement failed in Delaware, where Christine O'Donnell -- one of the most outspoken Tea Party activists in the country -- lost by double digits to Democrat Christopher Coons in Vice President Joe Biden's old Senate seat.
O'Donnell today blamed her loss in part on the mainstream GOP's initial refusal to back her candidacy after she pulled off an upset in the September primary.
"I think the only thing that really would have made a difference is if the Delaware GOP would have unified," she told "Good Morning America" today.
"We spent the good four weeks after the campaign reaching out to many Delaware prominent Republicans," she said. "By the time we got their support we had two weeks left."
The makeup of the Senate and House majorities are already cemented, but several races across the country are still too close to call.
In Palin's home state of Alaska, Republican U.S. Sen. Lisa Murkowski may win her write-in campaign, which would make her the first senator to successfully mount such a campaign since the 1954.
Murkowski was slated to lose her seat to Palin-backed Tea Party candidate Joe Miller, but an eleventh-hour surge pushed her ahead in the polls. Early this morning she held a majority of the vote with 41 percent over Miller and Democrat Scott Adams.
Recounts are a possibility in the Colorado Senate race where Ken Buck and Michael Bennet are locked in a dead heat and in Washington state, where Democratic Sen. Patty Murray holds a sliver-thin lead over Republican Dino Rossi.
ABC News' Jonathan Karl, Jake Tapper, Claire Shipman and Neal Karlinsky contributed to this report.