"I got a bunch of night-off jokes tonight," Bosh said. "I enjoyed it. Guys filled in and did their job."
Among the contributors off the bench was Greg Oden, playing his 11th game after being sidelined by knee trouble for 3 1/2 years. He went 3 for 3 for eight points with four rebounds in 13 minutes.
"I'm happy to be on the team," Oden said. "When I get a chance to play, I just don't want to mess up."
Heat guard Mario Chalmers had the highlight play of the first half, fetching a loose ball while seated at midcourt with his back to his basket, then flipping a pass over his shoulder to James to set up a fast-break basket.
The Heat also got to the rim often out of their half-court offense.
"They do a good job moving the ball, driving, kicking," Vucevic said. "They make plays for each other. They're very unselfish."
Orlando's Arron Afflalo missed his fourth consecutive game. He was out with a sprained ankle and is now recovering from a brief illness. ... At 42-14, the Heat have tied their best start through 56 games. They had the same record a year ago, when they went on to win their second consecutive NBA title. ... The Heat improved to 15-0 at home when leading at halftime.
ESPN.com's Michael Wallace and the Associated Press contributed to this report.