The two-time defending division champs had a four-game division lead entering play on Sept. 5, but have gone 8-14 since. They are 11-15 this month, with the 15 losses being their most in one month since the club was 10-17 in May 2002.
Oakland went 70-30 the past four Septembers -- the best mark in the majors.
Erubiel Durazo tripled in the fourth for the A's after Reed cost the designated hitter a homer with a leaping stop against the wall in center field. The ball would've cleared the fence, but Reed deflected it off the bottom of his glove and the ball landed on the warning track.
First-base umpire Doug Eddings initially signaled a home run. After Reed and Mariners manager Bob Melvin protested the call, the umpires met to review the play, then called Durazo back to third. He scored moments later on Jermaine Dye's sacrifice fly.
Eric Chavez scored on Durazo's hit after leading off the inning with a double.
Other than that inning, Meche shut down the A's lineup. He retired the side in order in the first and fifth and didn't allow more than one baserunner in the second, third and sixth.
He walked Chavez in the seventh to load the bases, then gave way to Ron Villone, who got Durazo on a foul popout.
Meche allowed two runs and six hits in 6 2-3 innings. He didn't know until recently that he'd never beaten the A's.
"I thought about it on the bench when I was done that it would probably be my first win against them," he said.Game notesOakland's Mark Kotsay singled in the third to extend his hitting streak to 15 games, an A's season high. ... Meche was 0-4 with a 4.78 ERA in his first eight outings vs. Oakland. ... The A's starters are 5-10 since Sept. 5 and have tossed six of fewer innings 12 times during that span.