Bobo said community-coordinated search teams go out every Saturday to look for Holly. Four search teams rotate through the weeks, but the Bobo family participates every week, going door-to-door in search for Holly.
Additionally, Bobo oversees posters, billboards, decals, business cards and prayer fliers in her community. She also encourages people to submit tips and information to email@example.com or people can call 1-800-TBI-FIND (1-800-824-3463).
"Every tip matters, even if we know it's probably not going to work out or the tip may be of false hope, still run it out to find out where it does end because then you know you have that answer, period," Caison said. "You can't just assume what the answer would be."
Caison is often frustrated by the presumption that a missing person either ran away or is dead.
"I always tell my families, without a body you can still have hope no matter what anybody tells you," she said. "They can't take that away from you, whether it's hope of them being found deceased or alive, still the ultimate goal is resolution."
When asked whether she still believes her daughter might be alive, Karen Bobo said, "I do. I've always felt that. That's what I'm going to continue to believe."
The Bobos are one of hundreds of thousands of families who are missing children, adults and elderly relatives. About 800,000 children are reported missing in the United States every year, according to the National Center for Missing and Exploited Children.
That's 2,000 children per day. The "vast majority" are recovered quickly, but the other families are left wondering.
Caison believes that the Cleveland women are not the only ones who are alive and trapped.
"I believe there's many," she said. "I've always believed that."
"There's a lot of people out there that need help," Caison said. "I know that if I were to get missing, I'd want to keep that hope alive knowing that people would never give up looking for me."
She hopes that the Cleveland case will give people a renewed sense of awareness so that more people can be rescued
"When you're afforded miracles like this one, it's just that much more proof that good is out there and that there are people that are taken against their will, there are people that are held captive, there is human trafficking," she said. "All of these things do exist so it's not out of the realm of reality."