One of the last people to see Brittanee was her friend Peter Broswick, one of the Rochester men who Brittanee visited at the Bluewater Resort Saturday night. According to the police report, two of the men told police she stayed only for about 10 minutes and left to return some clothing to another friend.
Knipes told ABCNews.com that the men, including Broswick, checked out of their hotel between 1 a.m. and 2 a.m. that night and drove back to Rochester.
"Sinister? I don't know," he said, pointing out that Rochester is a 16-hour drive from Myrtle Beach and the men may have had school or jobs they needed to get back to.
The others, according to a police report, told detectives that they had only met Brittanee, through Broswick, the night before at a night club. None of them, he said, are considered persons of interest at this time.
Broswick told ABCNews.com that he didn't have anything to do with Brittanee's disappearance and that they'd been friends for about two years.
Broswick's lawyer, John Parrinello, told ABCNews.com that Brittanee began hanging out with the men after several disagreements with the friends she was traveling with.
After Brittanee left the hotel, Parrinello said, the men went to a nearby college party, but left shortly after. Since they had to check out of the hotel the next morning anyway, they decided to just leave then and get a head start on their trip.
"All of these innuendos and inferences are to no avail," Parrinello said, adding that he was hired to be a go-between with Broswick, the media and the police.
Parrinello said the car the men had been travelling in has been searched and Broswick is scheduled to give a DNA sample at the request of the Myrtle Beach police.
ABC News attempted to reach the rest of the men Brittanee was with that day. Two did not immediately return messages and two others declined to comment.
"We already gave our statement to police," Anthony Schimizzi said. "We're not talking to anyone else."
Brittanee is believed to have her cell phone and her purse with her, Drexel said, but left her luggage behind in the hotel room.
"It's not like my daughter ... to leave her stuff," she said, describing Brittanee as a typical teenager who pays close attention to her clothes, hair and makeup.
Drexel said she does not believe her daughter has run away, but is pleading with her to call if she can.
"I want her to know she's not in any kind of trouble," Drexel said. "We just want her to come home."