Party Drug to Treat Depression?

Clinical trial of ketamine to treat patients with depression shows promise.
2:31 | 02/02/12

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Transcript for Party Drug to Treat Depression?
-- man whose story reflects that of so many people in this country a decade long battle with despair. Depression. Doctors have tried just about everything they could to treat him and then they turn to a drug with the notorious past. Not only did -- help in the change was immediate raising new hope. For millions of Americans suffering from depression and here's ABC's doctor Richard -- The first anti depressant I was honest -- so then prozac ran around like millions of the -- it's Christy -- who's suffering from depression. -- nothing worked you spend every day. And wishing that you weren't awake. Chris is girlfriend was there for the worst times. As always -- worry for me I'd come home was he going to be a violent. He had given up the idea of ever feeling better -- kill them. Help from the most unlikely of places a party. Sometimes called special K doctors call academy. But scientists have discovered that in a different form it has amazing potential. It took just one dose. Immediately I am I felt. Clear myself for the first time in months ahead I actually wanted to get up the next morning they really. -- -- -- The potential to be the biggest change in the treatment of depression probably in the last fifty years. Most -- -- -- depression target serotonin. Which -- on just 5% of the connections in the brain. But can -- mean tax on a chemical called glutamate which has ten times as many pathways. Rewiring the brain's capacity to feel so what's wrong with auto club tonight and say I'm trying to academy. -- -- -- -- -- But doctors are actively searching for drugs that work in a similar way. Chris has been taking an experimental drug that works like kittens for more than a year before he couldn't crawl at a -- -- Now he has hope. A -- A future. I can actually experience enjoying and relaxation. -- -- to take bad that deep. Refreshing breath track -- doctor Richard -- ABC news New Haven, Connecticut. Great to tell you about the surprising break through and after ten years of so much despair how wonderful to report something else -- truly happy ending here is a picture. Of Chris and his girlfriend now engaged. Planning to get married next year and -- the rest of their lives.

This transcript has been automatically generated and may not be 100% accurate.

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