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Below are some of the notable comments made Sunday on "This Week with George Stephanopoulos." Guests included Virginia Gov. Bob McDonnell, chairman of the Republican Platform Committee; Los Angeles Mayor Antonio Villaraigosa, chairman of the Democratic National Convention; ABC News' George Will; Rep. Donna Edwards, D-Md.; former Michigan Gov. Jennifer Granholm, host of Current TV's "The War Room"; Republican strategist Mary Matalin; and FOX News anchor Greta Van Susteren.

Governor Bob McDonnell

MCDONNELL: I would say that Governor Crist's endorsement adds one more vote in Florida, and that's it. He is wrong on every other point.

MCDONNELL: It's a general proposition to say we support human life. The rest of those details are up to the states and the people respectively, George, and that's simply not covered. It's something up to Congress and the states.

Mayor Antonio Villaraigosa

VILLARAIGOSA: With respect to the plank, I think Governor Crist said it very well, and that it is what it is. And maybe it's been there for 30 years. But it's time to take it out. The idea that we put in our U.S. Constitution an amendment that says that women can't get an abortion even in the case of incest and rape is way beyond the mainstream.

VILLARAIGOSA: The Romney/Ryan budget would extend the deficit 29 years. We wouldn't solve this deficit problem. The Romney/Ryan plan isn't the way to address the deficit, is not the way to address the economy. It will actually put us backward when you talk about the unemployment rate.

Powerhouse Roundtable

George Will

WILL: The ultimate irony of premium support is, it's a back-door, surreptitious way to begin the means testing entitlement programs, that is, to make the rich play more, is making it more progressive.

WILL: You young people, all five of you, don't have one of these yet. This is a Medicare card, which I got six years ago. I showed it to my doctor, he said, that's wonderful, George, now, we'll send the bills to your children. Now that's a funny way to run the state.

Mary Matalin

MATALIN: You know why I'm shaking my head? Because the Democratic gender gap with men is as great as the gender gap with women.

MATALIN: Let me tell you about Paul Ryan. He has the earnestness and the enthusiasm and the vigor of a young person, but he has an old soul, which means you're wise and responsible. So he does project maturity. He is an intellectual at the center of the House. He is the only one with ideas on the table. And he has done a lot for the ticket.

Jennifer Granholm

GRANHOLM: Romney is in a position of having to distance himself from his own platform. And it gets to the issue, the fundamental issue is, what kind of leader is he? Is he going to embrace what the Republican Party is all about, or is he going to flee from it? Choosing Ryan, I think, was his answer.

GRANHOLM: Mitt Romney has put a guy in congress who's been in charge of the obstruction of congress. So the president can point to them and say, they are the solution, they have caused the problem.

Rep. Donna Edwards

EDWARDS: But I think the problem that Mitt Romney has is that the things that people know about Mitt Romney, they don't like. The problem is the policy agenda for Mitt Romney that is saying to middle-class families, sorry, but you're on your own.

EDWARDS: There's a lot at stake for young people in this election. It's true, many of them have moved back home with their parents. But they're also drowning under a sea college loan debt. And they see that President Obama has actually been the one to put forward a plan for college students

Greta Van Susteren

VAN SUSTEREN: Everyone knows that there is a problem with Medicare. Every single person knows that it's just not sustainable. And the one thing is the American people want some ideas, they don't want to be told, oh, it's going to be OK. They don't want the talk. They want to see something is being done, a start - a program out there. I don't know if Paul Ryan has the best program out there, but he has got one on the table.

VAN SUSTEREN: In order to sell us on some big change economically, he has got to at least have a little bit of production record. And that stimulus bill, we all hoped that it would be like - you know, we all wanted the economy to go well, it just didn't quite work out that way.

Third Party in Missouri?

STEPHANOPOULOS: He mostly wants it to go away, Mary Matalin. And we're seeing Todd Akin - George thinks he might get out. I got that same sense while I interviewed the congressman this week, but since then he's dug in a couple of times. We have a new poll out this morning. He's now down nine points to Claire McCaskill in the Missouri race he was winning.

MATALIN: George, he may dug in, but he's not going to have a shovel to continuing digging. Because he's not going to have any money. George Will is right. We need to win Missouri. We're going to win Missouri. Ann Wagner is going to end up being our candidate. The party is going to get Ann Wagner in.

STEPHANOPOULOS: So you're just convinced that he's going to get out?

MATALIN: Or we'll run a third party, we'll run a write-in. We can do it. We have the money to do it. We are going to transfer the money. It's not as easy as - but it's a good state for Romney. And we'll get it back.

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