Oracle and Tapestry slip while Adobe and Sarepta advance

Stocks that moved substantially or traded heavily on Friday

NEW YORK -- Stocks that moved substantially or traded heavily on Friday:

Oracle Corp., down $1.96 to $54.51

The business software maker's fiscal second-quarter revenue fell short of Wall Street forecasts.

Adobe Inc., up $11.98 to $317.94

The design software company's fiscal fourth-quarter profit and revenue beat analysts' forecasts.

Wells Fargo & Co., down 57 cents to $53.79

Bond yields fell, which hurts banks' ability to charge more lucrative interest on mortgages and other loans.

Tapestry Inc., down 40 cents to $25.94

The maker of high-end shoes and handbags said the CEO of its Kate Spade business is resigning.

Sarepta Therapeutics Inc., up $31.58 to $132.05

The drug developer received regulatory approval for a muscular dystrophy treatment.

iHeartMedia Inc., up $1.08 to $15.64

Liberty Media is seeking permission to buy a larger stake in the radio broadcaster, according to the Wall Street Journal.

Exelixis Inc., up 17 cents to $17.82

The drug developer gave investors an encouraging update on its development of a cancer treatment.

Facebook Inc., down $2.64 to $194.11

The Federal Trade Commission could block the company from integrating its messaging apps, according to media reports.