Older Americans and other groups particularly vulnerable to the virus have had access to a third dose of the Pfizer and BioNTech vaccine since September. But the Food and Drug Administration has said it would move quickly to expand boosters to younger ages if warranted.
Pfizer is submitting early results of a booster study in 10,000 people to make its case that it’s time to further expand the booster campaign.
Pfizer’s new study concluded a booster could restore protection against symptomatic infection to about 95%, even as the extra-contagious delta variant was surging. Side effects were similar to those seen with the company’s first two shots.
A median of 11 months after their last Pfizer vaccination, trial participants were given either a third dose or a dummy shot. Researchers tracked any infections that occurred at least a week later, and so far have counted five cases of symptomatic COVID-19 among booster recipients compared to 109 cases among people who got dummy shots.
The current rules: People who initially received Pfizer or Moderna vaccinations are eligible for a booster six months later if they’re 65 or older, or are at high risk of COVID-19 because of health problems or their job or living conditions. Because the single-dose Johnson & Johnson vaccine hasn’t proven as effective as its two-dose competitors, any J&J recipient can get a booster at least two months later.
Also, anyone eligible for a booster doesn’t have to stick with their initial vaccination type and can get a different company’s vaccine, what’s called mixing and matching.
About 194 million Americans are fully vaccinated. Under today's policies, authorities already estimated about 2 of every 3 vaccinated adults could qualify for a booster within the next few months. Many who don't meet the criteria often score an extra shot because many vaccine providers don't check qualifications.
If the FDA authorizes Pfizer's request for expanded boosters, the Centers for Disease Control and Prevention then will make recommendations for how to use them.
Globally, boosters also are a hodge-podge. Some countries restrict them to older or medically fragile people while others have few restrictions. Israel, for example, has allowed Pfizer boosters for anyone 12 and older. Canada's health regulator on Tuesday authorized Pfizer boosters for people 18 and older.
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