A rep for the actress told ABC News that the "Jackie" star would like to attend the show, but can't because of her pregnancy.
The Oscar winner and her husband Benjamin Millepied announced they were expecting their second child last September. They are already parents to a 5-year-old son.
"Due to my pregnancy, I am unable to attend the Independent Spirit Awards and the Academy Awards," the statement read. "I feel so lucky to be honored among my fellow nominees and wish them the most beautiful of weekends."