COVID-19 updates: White House press secretary Jen Psaki tests positive

Florida Gov. Ron DeSantis said the state has filed a lawsuit against the Biden administration, arguing that the vaccine mandate for federal contractors is "unconstitutional."

"Florida companies, public and private, receive millions of dollars in federal contracts annually and will be negatively impacted by the unlawful requirements," a statement from Florida Attorney General Ashley Moody said.

DeSantis said in a statement, "The federal government is exceeding their power and it is important for us to take a stand because in Florida we believe these are choices based on individual circumstances.”

The global number of COVID-19 cases and deaths are now increasing for the first time in two months, largely driven by an ongoing rise in Europe that outweighs declines in other regions, W.H.O. Director-General Dr. Tedros Adhanom Ghebreyesus said Thursday.

The highest case increases in the last two weeks were in the Czech Republic (up by 234%), Hungary (up by 200%) and Poland (up by 183%), according to the W.H.O.

The director-general attributed ongoing infections "in large part" to inequitable access to tests and vaccines.

"Eighty-times more tests, and 30 times more vaccines, have been administered in high-income countries than low-income countries," Tedros said. "If the 6.8 billion vaccine doses administered globally so far had been distributed equitably, we would have reached our 40% target in every country by now."

-ABC News' Christine Theodorou

Hospital admissions have fallen by about 55% since late August, according to federal data.

But five states have seen at least a 15% increase in hospital admissions over the last two weeks: Alaska (21.7%), Colorado (15.9%), Maine (35.3%), New Hampshire (38.9%) and New Mexico (19.6%).

Alaska currently has the country's highest infection rate, followed by Montana, Wyoming, North Dakota and Idaho.

The U.S. reported approximately 1,600 COVID-19 deaths on Tuesday alone. Deaths are about 1.5 times higher in non-metropolitan areas than in metropolitan areas, according to federal data.

-ABC News' Arielle Mitropoulos

Colorado's available number of ICU beds is at the lowest point of the pandemic following a dramatic spike in hospitalizations and the winding down of extra beds added in the last surge.

Colorado currently has 1,191 COVID-19 patients, according to state data, and 29% of hospitals anticipate an ICU bed shortage in the next week. 

State health officials told ABC News that hospitals in El Paso County have turned away transfer requests over the lack of beds.

“We are continuing to move very much in the wrong direction,” Scott Bookman, the state’s COVID-19 chief, said at a briefing. 

-ABC News' Jeff Cook