The owners had not lost hope that the pup was alive and called out "Romeo! Romeo!" while on site, Latina Quotidiano reported.
Amazingly, they were were met with barking, according to the paper.
Firefighters who had been escorting the owners then immediately began to dig and were able to rescue the dog, the local paper said.
At first, Romeo appeared to be bewildered as he scampered down a mound of broken concrete and other debris, The Associated Press reported. But after he quickly took a few steps and sniffed his surroundings, he started wagging his tail.
Latina Quotidiano called the dog's rescue a sign of hope for those who lost everything in the Aug. 24 earthquake.
ABC News' Benjamin Gittleson, Clark Bentson and Jon Williams contributed to this report.