The team was held for about seven hours in the village of Nahuila, in the province of Alta Verapaz, north of Guatemala City.
The villagers said they didn’t want the shots, and later blocked a road and let the air out of the nurses' tires. A cooler and about 50 doses of vaccine were destroyed.
Police and local officials later negotiated their release.
“Other communities have refused, but what they usually do is draw up papers saying we went to offer to vaccinate them, and they take responsibility for refusing it," Sandoval said.
“A lot of people don't believe in the illness,” Sandoval said. “There is a clash of cultures.”
Guatemala has seen 566,636 confirmed coronavirus cases and 13,750 deaths from COVID-19.