The Federal Reserve's quarter-point cut, its first in a decade, was widely expected. But Chairman Jerome Powell disappointed investors by saying at a news conference the central bank had no plans for a long cycle of lowering interest rates. He called Wednesday's cut a "mid-cycle adjustment."
Powell was "less dovish than expected," said Jingyi Pan of IG in a report. Pan said share prices declines reflect "significant disappointment" that the Fed wasn't "embarking on the beginning of a rate cut cycle."
The CME Fedwatch Tool, operated by CME Group Inc., said investors expect only one more U.S. rate cut of one-quarter point this year, down from previous expectations of two.
Powell's comments "suggested that the Fed is largely undetermined in their next steps," said Pan.
The Shanghai Composite Exchange lost 0.6% to 2,914.07 and Hong Kong's Hang Seng shed 0.6% to 27,627.66. Sydney's S&P-ASX 200 lost 0.2% to 6,795.70 and benchmarks in New Zealand, Taiwan and Southeast Asia also retreated.
Tokyo's Nikkei 225 edged up 4 points to 21,525.85 and South Korea's Kospi gained 3 points to 2,028.44.
On Wall Street, the Standard & Poor's 500 index had its worst day in two months, falling 1.1% to 2,980.38. The index had hit an all-time high on Friday.
The Dow Jones Industrial Average lost 1.2% to 26,864.27. The Nasdaq composite fell 1.2% to 8,175.42.
The Fed hopes the rate cut will counter threats to the U.S. economy ranging from uncertainties caused by the nation's trade disputes to chronically low inflation and a dimming global growth outlook.
Fed officials had signaled their readiness to take action to help shore up the U.S. growth, which faces threats from a tariff war with China.
Wednesday's cut was the first since December 2008 during the global financial crisis, when the Fed slashed its rate to a record low near zero and kept it there until 2015. After that, the Fed went on to make nine quarter-point rate increases from December 2015 to December 2018.
The 10-year Treasury yield fell to 2.01% from 2.06% late Tuesday, a big move. The two-year yield, which is more influenced by the Fed's movements, rose sharply to 1.86% from 1.83%.
ENERGY: Benchmark U.S. crude fell 68 cents to $57.90 in electronic trading on the New York Mercantile Exchange. The contract gained 53 cents on Wednesday to close at $58.58. Brent crude, used to price international oils, lost 70 cents to $64.53 per barrel in London. It rose 42 cents the previous session to $65.05.
CURRENCY: The dollar gained to 109.13 yen from Wednesday's 108.78 yen. The euro declined to $1.1049 from $1.1077.