The strait is located at the mouth of the Persian Gulf and is crucial to global energy supplies, with about a third of all oil traded at sea passing through it.
Iranian Adm. Hossein Khanzadi told state TV on Thursday the 3-day maneuvers will start on Friday and extend as far as the Sea of Oman and the fringes of the Indian Ocean.
He said submarines, warships, helicopters and surveillance planes will participate in the drill, dubbed as "Velayat-97." The exercise will include missile launches from the vessels.
Iran regularly holds maneuvers in the strait.