In an effort to promote and prepare for the upcoming games, the Prince and Mrs. Obama and Biden will tour the grounds and participate in a sporting scrimmage event.
The Games, which first started in 2014, bring together wounded veterans to compete in sporting events.
The trio plan to meet with wounded veterans who are in recovery and rehabilitation programs. Though the prince will only be in the United States for one day, it will be a day packed full of meet-and-greets and tours, including a visit to the USO Warrior and Family Center, built for service members, military families, and caregivers, specifically those injured in battle.
Obama and Biden also hope to use the even to bring attention to their "Joining Forces" initiative, an effort to to raise U.S. support for veterans and their families though health, education and employment opportunities.
During the visit to the base they will also see a short scrimmage, similar to one at the Invictus Games.
The prince is also scheduled to meet with President Obama in the afternoon, the White House calling it "a sign of the enduring and special relationship that binds our two countries."
Prince Harry was also expected to attend an event at the British ambassador's residence, along with the directors meeting for the games.
The 2016 Games will be hosted by the U.S. in Orlando, Florida, at the ESPN Wide World of Sports Complex. ESPN is co-owned by by ABC News' parent company, the Walt Disney Company.
"I have no doubt... the USA will put on a great show — no pressure!" he said in the announcement video this past summer. "What better place to host such a great family event than Orlando."