Israel-Gaza-Lebanon updates: IDF orders evacuations in Beirut as huge blast hits city

The Israel Defense Forces issued another evacuation order for residents in southern Beirut suburbs late Thursday local time.

"You are located near Hezbollah facilities and interests, and the IDF will act against them in the near future," the alert stated.

The order comes amid heavy cross-fire. The IDF said Hezbollah fired approximately 230 projectiles from Lebanon into Israeli territory on Thursday.

Earlier Thursday, the IDF said its forces struck 15 Hezbollah targets in Beirut over the past day.

The U.S. State Department organized a second flight Thursday to evacuate Americans from Lebanon, spokesperson Matthew Miller said.

The flight departed Beirut for Turkey on Thursday morning with 134 passengers, Miller said during a press briefing Thursday.

Following Wednesday's charter flight out of Beirut, that brings the total number of American citizens and their immediate family members who have departed to 250, he added.

In the past week, the State Department has also been able to secure 1,400 seats for Americans on Middle East Airways commercial flights, according to Miller.

"While we don't know the total number of U.S. citizens who have left via the seats we have made available on commercial flights, we do know that a high percentage of those seats have been filled," he said. "We urge Americans to take advantage of these options now, while it is still safe to do so."

-ABC News' Shannon K. Kingston

Twenty-eight health care workers have been killed in Lebanon in the past 24 hours amid Israel's bombardment, the World Health Organization said Thursday.

"Health and humanitarian workers, including WHO staff, have done incredible work under very difficult and dangerous conditions with limited supplies. And yet health care continues to come under attack," WHO Director Dr. Tedros Adhanom Ghebreyesus said in a statement.

In southern Lebanon, 37 health facilities have been closed, he said. In Beirut, three hospitals have been "forced to fully evacuate staff and patients" and two others were partially evacuated, he said.

"Many health workers are not reporting to duty as they fled the areas where they work due to bombardment," the director said. "This is severely limiting the provision of mass trauma management and continuity of health services."

Emirates is canceling all regular flights to and from Iraq, Iran and Jordan on Friday and Saturday "due to regional unrest," the airline said.

The U.S. Federal Aviation Administration also issued a Notice to Air Missions on Thursday urging "airlines and pilots to use caution when flying in Israeli airspace."

-ABC News' Sam Sweeney and Ayesha Ali