A ship towed the U-shaped barrier from San Francisco to the patch in September to trap the plastic. But during the four months at sea, the boom broke apart under constant waves and wind and the boom wasn't retaining the plastic it caught.
"Hopefully nature doesn't have too many surprises in store for us this time," Slat tweeted. "Either way, we're set to learn a lot from this campaign."
Fitted with solar-powered lights, cameras, sensors and satellite antennas, the device intends to communicate its position at all times, allowing a support vessel to fish out the collected plastic every few months and transport it to dry land.
The plastic barrier with a tapered 10-foot-deep (3-meter-deep) screen is intended to act like a coastline, trapping some of the 1.8 trillion pieces of plastic that scientists estimate are swirling in the patch while allowing marine life to safely swim beneath it.
During its first run, the organization said marine biologists on board the support vessel did not observe any environmental impact.
Slat has said he hopes one day to deploy 60 of the devices to skim plastic debris off the surface of the ocean.