The new COVID-19 variant first identified in the United Kingdom could increase the trajectory of the virus in the United States, according to a report released by the Centers for Disease Control and Prevention on Friday.

Unless new mitigation measures are taken, the variant, known as B.1.1.7, is likely to become the predominant variant in the U.S. by March, the report warned. The CDC called for "universal compliance" with public health measures and more genomic surveillance to monitor new variants and mutations.

"Higher vaccination coverage might need to be achieved to protect the public," according to the report. While the new variant is not more deadly than the old one, it is thought to be more transmissible, meaning that it could lead to more cases, and ultimately more hospitalizations and deaths.

-ABC News' Sony Salzman contributed to this report.

Deaths from COVID-19 reached a grim new milestone Friday, with 2,00,905 fatalities reported around the world since the pandemic began, according to data from Johns Hopkins University.

The United States leads the world in COVID-19 deaths, with 389,581 fatalities, followed by Brazil, India, Mexico and the United Kingdom.

-ABC News' Rachel Katz contributed to this report.

Dr. Anthony Fauci called President-elect Joe Biden's promise to administer 100 million COVID-19 shots in the first 100 days of his term "quite feasible" during an interview with NBC's "Today" show Friday. He said he hopes the United States can get to 70% or 80% vaccination within several months.

Part of the distribution holdup, according to Fauci, has been careful prioritization by states. "If you have a dose, give it," he urged states. "Don't be so rigid as to those early designations."

Reaching those goals, however, depends on vaccine uptake. "When a vaccine becomes available, get vaccinated,” Fauci pleaded with the public.

-ABC News' Anne Flaherty contributed to this report.

U.S. President-elect Joe Biden has chosen Dr. David Kessler, former commissioner of the Food and Drug Administration (FDA), to help lead the federal government's COVID-19 vaccine initiative.

Kessler, a pediatrician and lawyer who headed the FDA from 1999 to 1997 under the Bush and Clinton administrations, will replace Dr. Moncef Slaoui, who is the current chief science officer to Operation Warp Speed.

Biden also announced several other appointees who will join his incoming administration's COVID-19 response team.

"We are in a race against time, and we need a comprehensive strategy to quickly contain this virus," Biden said in a statement Thursday. "The individuals announced today will bolster the White House’s COVID-19 Response team and play important roles in carrying out our rescue plan and vaccination program. At a time when American families are facing numerous challenges I know these public servants will do all that is needed to build our nation back better."

It's just over a week into 2021 and the United States has already seen its worst week on record for both COVID-19 infections and deaths.

In the first 10 days of the month, the country has recorded some 2.35 million COVID-19 cases and more than 28,000 deaths from the disease. That works out to be around 163 Americans diagnosed with COVID-19 every minute, and approximately one American death from the disease reported every 30 seconds, according to an ABC News analysis of data compiled by The COVID Tracking Project, a volunteer-run effort to track the U.S. outbreak.

The U.S. has not seen a day with fewer than 100,000 new cases in more than two months, with a record-high average of 243,000 newly confirmed infections every day. In the last week alone, that average of daily cases has increased by approximately 16.3%.

Sunday marked the 41st consecutive day with more than 1,000 fatalities from COVID-19 reported nationwide. The country's average of daily deaths jumped by 21.4% in the last seven days.

Meanwhile, more than 129,000 people are currently hospitalized with COVID-19 across the U.S. -- a number that has hovered around 130,000 for the last several days.

At the current rate, January could surpass December's staggering COVID-19 totals to become the nation's hardest hit month of the pandemic.

ABC News' Brian Hartman and Arielle Mitropoulos contributed to this report.