The U.S. death toll from COVID-19 continues to climb in the weeks following the end-of-year holidays. Fatalities from the disease nationwide are currently 25% higher than at any other time during the coronavirus pandemic, according to The COVID Tracking Project, a volunteer-run effort to track the U.S. outbreak.

"For scale, COVID-19 deaths reported this week exceed the CDC's estimate of 22K flu-related deaths during the entire 2019-2020 season," The COVID Tracking Project wrote on Twitter Thursday.

There were 3,915 deaths from COVID-19 registered nationwide on Thursday, well above a seven-day average that continues to rise. However, COVID-19 cases and hospitalizations were under the seven-day average on Thursday.

The one bit of good news highlighted by The COVID Tracking Project was that hospitalizations are leveling off. Still, there are 128,947 people currently hospitalized with COVID-19 in the United States, much more than at any other time during the pandemic.

The COVID Tracking Project singled out Alabama, Arizona, California and Florida as particularly concerning locations right now. Arizona currently has the worst per-capita case numbers in the world, according to the project.

A newly identified variant of the virus that causes COVID-19 may have emerged in the U.S. in May and could be one of the predominant versions circulating now, researchers at Southern Illinois University found.

Just because a new variant has emerged doesn't mean it's inherently dangerous, experts cautioned. It’s unknown if this new U.S. variant is more transmissible and deadly, but scientists say they are monitoring and continuing to study newly emerging viral variants. On Wednesday, researchers at Ohio State reported two newly identified ones. On Thursday, researchers at Southern Illinois University said they also identified a new variant, which is likely the same as the two identified in Ohio.

Now, researchers at Southern Illinois University are sharing even more details about this U.S. variant, which they are calling 20C-US. Origins of this variant can be traced to May 2020 from a sample in Texas, they said.

The 20C-US variant appears to be widespread in the Upper Midwest and comprises roughly 50% of the samples in the U.S., said Keith T. Gagnon, coauthor of the study and associate professor at Southern Illinois University.

"Let’s not get overly excited -- but be diligent," Gagon said. "Here it was, underneath our noses, for months."

“It doesn't look like it’s going to get in the way of vaccines," Gagnon added. 

ABC News’ Sean Llewellyn, Eric Strauss and Sony Salzman contributed to this report.

Texas, home to about 29 million people, has become the first U.S. state to administer more than 1 million vaccine doses, Gov. Greg Abbott said.

Texas has 2,040,751 confirmed cases and at least 31,277 fatalities, according to real-time data collected by Johns Hopkins University.

Texas’ Harris County, home to Houston, ranks No. 5 in the country for the highest number of confirmed cases, behind Los Angeles County, California; Cook County, Illinois; Marciopa County, Arizona; and Miami-Dade County, Florida.

ABC News’ Gina Sunseri contributed to this report.

The United Kingdom will ban arrivals from several South and Central American countries beginning Friday, following evidence of a new variant of the novel coronavirus from Brazil, British Transport Secretary Grant Shapps announced Thursday.

The U.K. government will ban arrivals from Argentina, Brazil, Bolivia, Cape Verde, Chile, Colombia, Ecuador, French Guiana, Guyana, Panama, Paraguay, Peru, Suriname, Uruguay and Venezuela, according to Shapps.

Travel from Portugal to the U.K. will also be suspended given its strong travel links with Brazil, Shapps said.

ABC News’ Christine Theodorou contributed to this report.

It's just over a week into 2021 and the United States has already seen its worst week on record for both COVID-19 infections and deaths.

In the first 10 days of the month, the country has recorded some 2.35 million COVID-19 cases and more than 28,000 deaths from the disease. That works out to be around 163 Americans diagnosed with COVID-19 every minute, and approximately one American death from the disease reported every 30 seconds, according to an ABC News analysis of data compiled by The COVID Tracking Project, a volunteer-run effort to track the U.S. outbreak.

The U.S. has not seen a day with fewer than 100,000 new cases in more than two months, with a record-high average of 243,000 newly confirmed infections every day. In the last week alone, that average of daily cases has increased by approximately 16.3%.

Sunday marked the 41st consecutive day with more than 1,000 fatalities from COVID-19 reported nationwide. The country's average of daily deaths jumped by 21.4% in the last seven days.

Meanwhile, more than 129,000 people are currently hospitalized with COVID-19 across the U.S. -- a number that has hovered around 130,000 for the last several days.

At the current rate, January could surpass December's staggering COVID-19 totals to become the nation's hardest hit month of the pandemic.

ABC News' Brian Hartman and Arielle Mitropoulos contributed to this report.