"My mother is staying with us now and we'll all go down the street to Matt Damon's house," the Gone Girl star told US Weekly. "We're all invited. Matt and my family are all like one big extended family for Thanksgiving. I'm looking forward to it a lot."
Affleck, 42, and Damon, 44, both hail from Massachusetts and attended Cambridge Rindge and Latin School together growing up.
"This year we're going to Matt's house, but usually I cook and Casey [Affleck, Ben's brother] and his family come over," Jennifer Garner told the magazine. "This year Casey is going to be in Boston and we'll be home."
Affleck and Garner, who have been married for nine years and have three children, live in Los Angeles.
Garner said she won't go empty-handed to Damon's house. "I'll still cook some stuff. Ben and the kids want me to take my grandmother's sweet potato pudding so I'll make that," she said.
Affleck also said he's bringing something over.
"I know I'm not cooking!" he said. "I'll bring some wine for sure -- wine will be flowing -- but I'll be focused on the turkey. I know I'll be eating a lot of turkey at Matt's house."