Some of Aniston's rom-coms have been hits, like "Marley and Me" and "The Break-Up." Others missed. Remember "He's Just Not That into You," or "Rumor Has It"?
But if Aniston hasn't pushed the envelope onscreen, she has done so for magazine covers. Appearing nude on the cover of GQ in January 2009, she told the magazine she feels more comfortable with herself now than in her 20s or early 30s. "I'm healthier. I'm more at peace in my mind and with my body," she said.
Now in her 40s, she seems to be ready to join other actresses who have bared all on screen after turning 40. Sandra Bullock, Mary-Louise Parker, Marisa Tomei and Kathy Bates all waited until after 40 to shed their clothes on screen. Diane Keaton was nearly 60.
"It's a way of reinventing oneself and reviving a career, UCLA film professor Vivian Sobchack told ABCNews.com. "It's an assertion of I'm still viable, I'm still here damn it, I'm still erotic and I still have sex appeal."
Markovitz said he believes Aniston is "just as vibrant as she's ever been." But he said she should use her experience and her long-time audience to stretch a bit. "Anything that shows a slightly darker side or more thoughtful side would be really cool," he said.