He said the two have agreed to disagree on Sheen's getting help and becoming sober.
"I wrote and finished this book before all of the latest chapters in Charlie's life where unfolding," Lowe said. "He knows my position. I know his position. But I respect a guy that's like, 'Hey, man, it's my life. Live it the way I live it.'"
As for Lowe, he eventually married make-up artist Sheryl Berkoff in 1991.
"I say in the book when I was a young punk and you would have asked me what the best thing that ever could have happened to me, I would have said getting a Martin Scorsese movie," Lowe said of Berkoff, 49. "But God had other plans. He gave me Sheryl. And she is the best thing that ever happened to me."
Lowe taped the interview with "Good Morning America" Monday morning, hours after the news that Osama bin Laden had been killed. Lowe said he was compelled to go and pay his respects after he heard the news at dinner.
"I went to Ground Zero," he said. "I went to Times Square. And as I was walking through the crowd and just being with people and sort of being a part of that moment, the firefighters hugged me and asked me to get up on top of the rig with them," Lowe said. "It was really emotional and just great to be part of this amazing moment."
Lowe was on the American Airlines flight 11 days before it would eventually crash into the Pentagon on 9/11. "It was a dry run with the 9/11 hijackers surrounding me in the cabin, same crew," Lowe said.
He said he knew the crew well, often taking the flight from Washington, D.C.'s Dulles International Airport to Los Angeles International Airport while filming "The West Wing."