But if cries are associated with certain actions over and over again, like being put down or spitting up, it's a good idea to check with a doctor to make sure nothing else is wrong.
If parents notice their baby has a weak cry, a weak suck, yellow skin -- which can signal jaundice -- or a fever, it's time to call the pediatrician, Besser said. And remember, no question is silly.
Find out everything you need to know about newborns from feeding to sleep to colic on today's ABC News health tweet chat moderated by Dr. Richard Besser, chief health and medical correspondent for ABC News. Besser will be joined by OB-GYN and pediatric experts from around the country to answer your burning questions on what it takes to keep your baby happy and healthy -- and you sane -- in the first three months of your baby's life.
The Twitter conversation starts today at 1 p.m., ET and runs for an hour. To learn how you can join in or just follow along, click here.