Lincoln voted for the health care bill and touted that vote heavily in her television commercials. Halter, however, also supported Obama's health care plan and unlike Lincoln, he also backed the option of a government-run health insurance plan that would compete with private insurers, a more liberal option that was stripped from the health care bill in the Senate to garner the votes of moderate Democrats.
Voters interviewed by ABC News overwhelmingly demonstrated anti-Washington sentiment prevalent across the rest of the country.
"I think people generally are unhappy with how Congress as a whole has behaved and I think what we'll see nationally is a lot of incumbents will be voted out of office, regardless of what party they're in," voter Roberta Monson said.
Another voter, Becky Dugan, said she supported Lincoln but understood the frustration among her peers.
"I like the direction the country is going. I like that we're in the direction of taking care of people," she said, adding that many people are "just frustrated. And I think when the economy has a downturn and we get worried, that frustration is an expression of that worry. More worry. Fear."
ABC News' Devin Dwyer and Andrew Fies contributed to this report.