Since 2003, the first lady has served as ambassador for Heart Truth, an organization to promote awareness of heart disease. This year she's proud to say that there were approximately 17,000 fewer deaths from heart disease.
Bush gives credit for the drop to the National Heart, Lung and Blood Institute, and to the Red Dress Project, for getting the word out. One of the project's main goals has been to get American women to realize that it isn't just a man's disease.
Unlike men, when women experience the symptoms of heart disease such as pain in the jaw, pain in the neck, pain in the left arm, pain in the center of the chest, a burning sensation in the back, extreme fatigue and difficulty breathing, they don't immediately get help.
"It's very important, if you have any of these symptoms, to get to the hospital immediately," Bush said. "And don't be embarrassed. If it isn't a heart attack, you know, there's no reason to be embarrassed."
"I doubt I would be standing here if I hadn't quit drinking whiskey and beer and wine and all that," President Bush told ABC's Martha Raddatz in an interview earlier this year.
The first lady spoke to Sawyer about how difficult it was for her being married to her husband during his drinking days in Texas. "It's very hard. Well, I did say things, of course, absolutely," Bush said.
"He knew what I thought about it and he thought that too. I mean he wanted to quit and any time anyone quits drinking or any other habit, they do it because they do it. I mean ... you have to do it yourself."
After making the decision to quit, it took "a few years" to stop for good, in which time Bush says his friends helped him to stop.
"I was really very proud of him, really proud of him. It's not easy. And we lived in west Texas, where drinking was a very big part of everyone's social life in a sort of Wild West, Texas town."