But the tight-lipped guests have finally opened up, including the bride's uncle, Roger Clinton, who said his niece was a "beautiful woman and her husband is one of a kind."
There were several memorable toasts, including a heartfelt one from the former president, but Mezvinsky stole the show.
"Marc spoke so movingly about his love for Chelsea," Daily Beast editor-and-chief Tina Brown said on "Good Morning America." "He locked eyes with her the whole time."
Mezvinsky talked about how blessed he was to have met Clinton, Daily Beast reporter Jacob Bernstein said, and how she had changed his life.
Although their honeymoon destination is a closely guarded secret, the newlyweds spent Sunday night in the Pierre hotel in New York City, Brown said on "GMA."
Guests received gift bags filled with wine from a local vineyard, pretzels, peaches and a note from the bride and groom. Neighbors received a bottle of wine for their troubles, hand-delivered by Rafanelli.
As far as who was there to witness it all, the big names the media had buzzed about for weeks -- Oprah Winfrey, Barbra Streisand and Steven Spielberg -- were not in attendance, perhaps not even invited.
"The funny thing about it was that the more they declared they wanted a private, really intimate family wedding, the more the rest of America wanted it to be something more than that," Brown said. "They did not succumb to the celebrity hype."
Two longtime friends, actors Ted Danson and Mary Steenburgen, were among the prominent names who did make the guest list, which included Bill Clinton's close friend and former White House adviser Vernon Jordan, and former Secretary of State Madeline Albright.
The Astor Courts Estates, which was previously for sale and then taken off the market in preparation for the big day, is back on the market. Realtors hope the recent attention will attract a buyer to scoop up the $12 million historical estate.
Brown said the joyous event came at a good time for the nation, which has been beat down by two wars and a crumbling economy.
"We almost could erase the 10 years since and think ourselves back to that moment when we were all kind of better off [during the Clinton era]," Brown said.
With toasting, dancing and all the wedding traditions, Bratten of Brides magazine said, America got a much-needed lift.
"No matter what is going on in the world," she said, "there is love."