Funny woman Molly Shannon, best known as a regular cast member on "Saturday Night Live," may be able to induce laughter like nobody's business, but her allergies induce reactions of their own.
"I have bad cat allergies," Shannon, 43, said on the CW11 Morning News in New York. "I'm one of those people if I go to somebody's house, even if I don't see the cat, I start wheezing or I get hives. I'm just very sensitive."
Shannon's father and younger son have allergies as well. She has been a spokeswoman for the Allergy and Asthma Foundation of America, raising awareness about allergies.
Shannon's career at "SNL," where she was the longest featured female cast member and had several recurring roles such as licensed joyologist Helen Madden and quirky Catholic schoolgirl Mary Katherine Gallagher, led to more featured parts in films. But her allergies posed a problem on the set of a recent film, "Year of the Dog."
"I didn't tell them, but we were in preproduction one day and I broke out a little bit because of the dog so I told them and they were like what?!?" Shannon told The Cinema Source magazine. "So I went to an allergy doctor and got all this medication but I never had to use any of it. I'm much more allergic to cats."
Serena Williams has continually wowed the tennis world with her skills, physical prowess and unique style since she rose to fame 10 years ago.
Currently ranked sixth in the Women's Tennis Association, the 5 feet 10 inch' beauty has made media headlines for her wins and her flamboyant fashion on the court.
She and older sister, Venus, have battled for the No. 1 ranking several times since both came on the tennis scene in the late '90s.
Even when a series of leg and ankle injuries led her to drop out of the top 100 ranking in mid 2006, Williams stayed in the spotlight with celebrity appearances, charity work and her fashion designs. Williams started her own fashion line Aneres -- Serena spelled backward -- and says on her official Web site that she hopes to continue with fashion after her tennis career.
But Williams can't beat everything -- she's allergic to peanuts. She falls in the approximately 1 percent of the population with a peanut allergy. According to the U.S. Olympic Web site, Williams says she's also allergic to crazy people.
Drew Barrymore, a gifted and versatile actress, has as eclectic collection of allergies as she does film roles.
Barrymore, 33, is allergic to garlic, according to a 1997 article in the Houston Chronicle, as well as coffee, bee stings and perfume.
Also a vegetarian, Barrymore said that eating "can be a major pain for me."
Barrymore, whose first major role was in Steven Spielberg's "ET" in 1982, and who went through bouts of partying and drug abuse in her adolescence, has blossomed into a career as an established actress and producer with huge box-office appeal.
Though her production company is named Flower Films, flowers and pollen are not among her list of allergens.
If Neko Case wasn't a musician, she knows what she might be.
"If I ever got out of music, I'd go back to school to become a forest ranger," Case, 37, told Fab magazine. "I've always wanted to be the lady with the jeep and the dog who works at the national forest service. I'd let the animals run free."